Megalophallus Hypoxia Growth Key.

Hypoxia induced SM growth could in theory account for some of the improved EQ from doing PE.

See I’m not really sure I agree. I think that more tissue growth will slowly stretch the tissue.

When I was a sophomore in high school, I used steroids one year and within 3-4 months I had SEVERE stretch marks. I’m talking thick and purple and about 4 inches long. A lot of them. And it wasn’t because I pulled very hard on the skin for a day or two straight. It just the rather quickly build up of tissue under the fascia per several months. The fascia expanded to its limit and then tore in several places thus the stretch marks.

My sister got up to a bodyweight of 350lbs. Then she lost 200lbs and still has INSANELY stretched out loose skin on her arms and stomach. The skin was permanently deformed because of very slow and gradual adipose tissue under it.

I definitely think that growth of tissue even at a very slow rate has the ability to permanently deform collagen/elastin bonds.

Is getting a bigger penis really worth all of this? Really?

Playing russian roulette with your dick.

I was like that too when I discovered PE, then I stopped gaining due to rappid tissue conditioning.

I’ts better to play it safe.

Is doing anything dangerous or unnecessarily TIME consuming or harmful in any way worth a bigger penis? Absolutely not.

Is using our combined knowledge and experience to talk about what exactly causes growth and why megalophallus occurs and what triggers breakthroughs worth it? I think so.

The whole purpose of this thread was basically “hey, there are guys walking around with massive penises that they developed within a month or year. In some cases a week. How does that happen?” Lol

It’s all good mate, guys are just voicing their concerns because they don’t want anyone to hurt themselves.

Keep up with the research, there are lots of threads here on the subject as well as plenty on the other main PE forums.

I wanted to post this as a thread but can’t so I decided to post it here to keep the conversation alive.
As we all know clamping has been an advanced PE exercise for many years. Today I want to talk about it and why I think it may be the best exercise out there. I feel people keep ignoring clamping because of the potential danger of being an advanced exercise and because it does not yield results to all, probably because people do not do them properly just like jelqing.

The main factor for which clamping produces growth isn’t through the expansion alone but through the activation of Hypoxia Inducible Factor (HIF) so if your penis just experiences clamping with fresh blood all the time chances are you won’t get the effects of HIF. I believe this is what happens in low flow priapism where we know that there is more isquemia than in high flow priapism. There have been 4 cases that I have found showing increased penis size as a secuela:




And one case of a person that has done clamping in a way:

All these studies serve as proof for penis enlargement the question is the mechanism. I believe that the answer is HIF this could explain many things into why some people gain and others don’t. HIF is activated with hypoxia and it causes:
1.- Extracellular Matrix Remodeling: Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by Inducing P4HA1, P4HA2, and PLOD2 Expression in Fibroblasts - PMC

2.- Enhances transcriptional activity of androgen receptor: Hypoxia enhances transcriptional activity of androgen receptor through hypoxia-inducible factor-1α in a low androgen environment - PubMed

3.-Enhances angiogenesis: Hypoxia-Induced Angiogenesis - PMC

Now how does this apply to PE well for example in jelqing some people might be better at retaining blood thus activating HIF and experience growth while others try to enter fresh blood. It could explain why studies show noose extenders work and these cause mild hypoxia at the noose site. It could explain why some clampers gain when they retain unoxygenated blood while others worry more about expansion and fresh blood. It could be the reason why hanging works for some and not others because of the wrap which causes hypoxia for some. This could be the reason why people notice that masturbation affects gains, the increase in androgen receptors could use the excess testosterone from masturbating once a week. Also most of these patients had these episodes in puberty so it could be that that specific time frame is crucial for HIF to give its best results.

Interesting, Miguel.
I wonder if we can somehow compile the results from clampers on whether they get to hypoxia or avoid it vs. their gains and also their age.

BTW, the 4shared links don’t seem to have valid content.

Ok sorry for the links here are the four studies reporting priapism induced Hypertrophy:
https://drive.g oogle.com/file/ … iew?usp=sharing
https://drive.g oogle.com/file/ … iew?usp=sharing
https://drive.g oogle.com/file/ … iew?usp=sharing
https://drive.g oogle.com/file/ … iew?usp=sharing

And one case of a person that has done clamping in a way: https://drive.g oogle.com/file/ … iew?usp=sharing

Thanks for posting those links. I’ve always thought megaphallous was the true documented example of enlargement anyone needed. It can be done in the human body because it HAS been done in the human body.

I’m torn on the conclusions to draw on this. We know occlusion training works for muscle hypertrophy and we know endurance athletes train or sleep at altitude or in hyperbaric chambers because low oxygenation cause positive adaptations in the body. And we have the SyFy Channel names mega-phallus to show it works.

The part I get confused on is I thought these were non-ishchemic (sp) priapisms, That is fresh oxygenated blood continued to trickle in but couldn’t escape, much like traditional clamping. And we know some mega phallus suffered experienced impotence as a result.

After doing a longer decon break I’ve really been converted to the IPR theory. Which lead me to read these studies again. I can’t find it explicitly stated but it appears that in most cases these were not daily occurrences but irregular extreme reactions. Which would mean that after stimulus they had time to remodel or mitosis etc.

Also the threshold for “priapism” is 4hours. These guys were well past that point, well past. I think the mindset in traditional clamping was always I’ll do x number of 10m sets avoid cell death and eventually reach the trigger point in a controlled environment. My worry is there maybe a “threshold” point at 4+x number of hours for hypoxia growth to occur and reintroducing oxygenated blood blunts that trigger.

If that were the case a single workout of five or more hours once a week to once a month would more closely resemble the megaphallous growth experience than six days of 3-6 10 minute sessions.

Obviously that’s riskier.

At which point someone invariably pops up with sage words like “you only have one dick! It’s not worth it.” That’s not unreasonable but in order to get exceptional body response you have to induce adaptation that is extreme enough to trigger the response—or stay home.

I’m not saying clamp off for six hours straight. BUT the 10m mark is conservative. There’s still fresh blood leaking in when you clamp. I just wonder if a 5+ hour marathon of 20 minute sets followed by a week or two off might not be a more speedy regime.

Just thinking out loud.

Well it seems that all the cases cited in the literature deal with patients who have sickle-cell disease which itself contributes to the mechanisms causing priapism. It does show that priapism will induce enlargement of the CC tissues. (Good thing for the one guy who wanted his penis reduced because his girlfriend compained but then she got used to it).
I guess the question needs to be - how long can you sustain hypoxia to contribute to this growth without causing necrosis? (there was this one thread on here where the guy strangled his penis and asked for help, but by the time he decided to get the ER it was too late, and they had to amputate his penis).

Interesting but scary territory…

Do you really think the body likes anything extreme? The responses you’re talking about are the bodys’ way of trying to defend itself.

Ok in the first example the patient started at 7 and ended by 17. Episodes were once or twice a year and last 4-16 (16!) hours. By 13 he knew he was large at age 13.

His function was fine and the reason he was seeking medical help was because it was painful for his wife during sex—not because of impotence.

One day once or twice a year? It makes wonder if there’s a balance between both the extreme length of the “session” and the long down time between episodes.

Thanks for posting.

Jimbob5, well yes, exactly. It doesn’t like it, it sees it as a threat, so it adapts.

Or is that what you meant?

I have tried to read all the cases involving clamping and have tried it but got scared due to possible fibrosis and impotence. I feel like I might have clamped too much and tried other routines like jelqing that messed my EQ. But after some time my EQ got better with my girlfriend and it seems I had more of a psychological issue than a physical one. So I’m trying to clamp again with HIF in mind. I feel like my penis is much more resistant to Hypoxia than before because it doesn’t get as discolored meaning purple. I will try with one day on and the other off since that is said to give gains to some and is what redzulu recommends and it seems he has experience but after 6 months. If I don’t see any gains I will try the approach of more time and bigger breaks to see how that works out. I will try to make a Thread involving all the people that claim to have gained through clamping and those that didn’t.