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Paper sheds light on conditioning/deconditioning

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Oh, I forgot one of the most important things. There is a new google search engine for research papers called google scholar.

It is at scholar.google.com

It is invaluable.


-Still bitter the y2k bug was a dud.

-My dear boy, do you ask a fish how it swims? (No.) Or a bird how it flies? (No.) Of course not. They do it because they were born to do it...

Hobby, I think “stiffness” is exactly what you’re saying. Mathematically, it’s the slope of the stress/strain curve (also called Young’s Modulus)—essentially, how far something stretches when subjected to a constant load.

The paper says stiffness increases with exercise, and decreases with immobilization. This supports the notion that rest reduces stiffness and allows greater elongation once exercise is resumed. This supports the value of deconditioning.

Tube,

I’ve only had one course in Mech-E. Got to stress-strain but not to strain tensors. Can you suggest some reading?

Thanks also for finding those other papers. It looks like I’ve got some reading to do.


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Tube,

Any chance you can find this one:

Harris AK, Stopak D, Wild P. Fibroblast traction as a mechanism for collagen morphogenesis. Nature 1981;290:249-51.

I’m not part of a university, but I can try my local library. If you can find it more easily, please let me know.


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Interesting that you mention it. Several major universities are (harvard, yale, columbia,etc) boycotting natures unreasonable pricing and institutional rules for “online access”. My uni is included. I tried finding that same article. It only applies to online access though. I will get the print version and see what I can do.


-Still bitter the y2k bug was a dud.

-My dear boy, do you ask a fish how it swims? (No.) Or a bird how it flies? (No.) Of course not. They do it because they were born to do it...

Awesome. Thanks. I know that fibroblasts generate collagen in response to stress, but I don’t know what happens next and whether the new collagen can help create new length. I suspect (read, “hope”) it does.


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A few more good quotes from the article:

Quote
Normal, physiological tendon and ligament strains are in this approximate range (26,27), and the literature suggests physiological and failure strains remain relatively constant between different tendons and ligaments, across species, and with age (16,19,26-28).

I found these two to be very interesting:

Quote
Previous investigations have shown that load magnitude affects bone remodeling more than the number of loading cycles (34). However, similar studies have not been performed for tendons and ligaments. Load magnitudes and number of loading cycles must be better characterized, and cross-sectional area, modulus, and failure stress need to be measured at intermediate time points during exercise and immobilization/remobilization studies

Quote
Changes in structural properties reflect both geometric and material property changes. Tendons and ligaments can therefore adapt to increased or decreased mechanical loading by adjusting their size, their material properties, or both. Our model takes into account changes in cross-sectional area, a geometric property, and changes in modulus, a material property.


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