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The Penis (smooth) Muscle Theory

Originally Posted by northof60
Http://www.cascadebio.com/index.cfm…Content&CID=543

Now these products are for scientific purposes NOT human consumption but still, if you look at the ingredients doesn’t it strike you as something that could have possibilities down the road?

I do find it interesting and I have investigated this. The real key is not the vitamins and amino acids but the fetal bovine serum. It is the blood of cow/bull fetuses and it contains natures growth hormone cocktail. Problems with this approach are that you would never want to inject cow blood into your penis and that the growth environment of cells in media is very different from those in tissue. Tissue culture cells, or cells in petri-dishes are usually monoclonal or one cell type and they just divide away without differentiation. It might be very difficult to induce the proper smooth muscle tissue differentiation within the penis but I really don’t know.

There is a synthetic version of fetal bovine serum and I have never found the ingredient list although I have not checked the patent. We wouldn’t want to use this on ourselves either but it would be good to know what it contains.

You spoke correctly, PS. Megalophallus — the monster cock condition — results from a loss of tunica elasticity, which in turn results from priapism episodes.

Originally Posted by penismith
Tissue culture cells, or cells in petri-dishes are usually monoclonal or one cell type and they just divide away without differentiation. It might be very difficult to induce the proper smooth muscle tissue differentiation within the penis but I really don’t know.

But doesn’t the bovine serum simply induce growth regardless of the cell type or number of cell types present? I would think the major challenge would be to keep the serum local (which is not a problem in a petri dish).

It just blows my mind that the major drug companies aren’t dedicating themselves to find a cream or injection that actually promotes penile tissue growth. There are 3.5 billion men on this planet who would fork out large portions of their annual salary to have a larger penis. We can put men on the moon and cure deadly diseases but the only thing men get out of it is shampoos that kill our sperm. We are getting the shaft (pardon the pun).

Originally Posted by northof60
But doesn’t the bovine serum simply induce growth regardless of the cell type or number of cell types present? I would think the major challenge would be to keep the serum local (which is not a problem in a petri dish).

It just blows my mind that the major drug companies aren’t dedicating themselves to find a cream or injection that actually promotes penile tissue growth. There are 3.5 billion men on this planet who would fork out large portions of their annual salary to have a larger penis. We can put men on the moon and cure deadly diseases but the only thing men get out of it is shampoos that kill our sperm. We are getting the shaft (pardon the pun).

Yes, that is true, you can grow many cell types in FBS (fetal bovine serum). What I meant by monoclonal is that people generally grow one cell type at a time in any given dish. Growing tissue in an artificial environment (in vitro) is quite difficult. In the context of a penile tissue, FBS might not induce growth in an adult male if you injected it but I really don’t know. The closest thing I can find on the subject is this thread:

anabolicminds.com/forum/igf-1-gh-sl…nis+enlargement

I sure as heck won’t be injecting anything into my dick, though. Also, IGF is just one of many growth factors in FBS.

I would love to pick the brains of some of the better pharmaceutical company principal investigators.


Last edited by penismith : 05-15-2006 at .

If a doctor really wanted to grow a penis, rather than just do surgery to screw up a guys dick and make money, is it not possible to: chemically or surgically weaken the Tunica and then pump?

If you could perforate the Tunica with 1000 tiny holes per square inch and then pump before it is healed you could evenly distribute the size gains.

Penismith,

For the record and to avoid devil’s advocacy :) , I don’t doubt the tunica is an important limiting factor. My point is that it is probably one of at least a couple. Inside the CCs, the smooth muscle operates within sinusoidal spaces made of collagen. Those spaces are defined by extensions of the inner layer of the tunica that form a lattice structure within the CC space.

My belief at the present moment is that length is limited by a combination of 1) tunica, 2) internal collagen structure of the CCs, 3) smooth muscle, and 4) other stuff (veins, arteries, nerves, skin …).

Guys whose BPEL is 2” longer than their FSL (which at least one guy has reported) are clearly not tunica-limited, IMO. They are somehow volume-limited. The contents of their CC cannot expand to fill the entire envelope that the tunica provides.

The point is, it’s all got to grow to realize BPEL gains.

Regarding the Peyronie’s article you posted, which I referred to above, it would be very interesting to see whether guys who received the venous transplants can continue to grow essentially at will by continuing to pump, or whether their growth is largely limited to just reclaiming lost length induced by the disease.


Enter your measurements in the PE Database.

Originally Posted by all4show

If a doctor really wanted to grow a penis, rather than just do surgery to screw up a guys dick and make money, is it not possible to: chemically or surgically weaken the Tunica and then pump?

If you could perforate the Tunica with 1000 tiny holes per square inch and then pump before it is healed you could evenly distribute the size gains.

It would certainly make our lives easier. THe problem with it is that the tunica would probably heal from the 1000 cuts to become stronger than it was originally, and the rate of healing would probably exceed the rate of tissue generation within the CC space. You might get a little length, or maybe not. Sometimes tissues shrink when they heal.


Enter your measurements in the PE Database.

Originally Posted by all4show

If you could perforate the Tunica with 1000 tiny holes per square inch and then pump before it is healed you could evenly distribute the size gains.

Like an dick-sized iron maiden? http://en.wikipedia.org/wiki/Iron_m…rture_device%29


regards, mgus

Taped onto the dashboard of a car at a junkyard, I once found the following: "Good judgement comes from experience. Experience comes from bad judgement." The car was crashed.

Primary goal: To have an EQ above average (i.e. streetsmart, compassionate about life and happy) Secondary goal: to make an anagram of my signature denoting how I feel about my gains

Mgus, that may hurt a little.

Modesto,

Can you create a theory (similar to LOT) for the FSL and EL?

Originally Posted by all4show
If a doctor really wanted to grow a penis, rather than just do surgery to screw up a guys dick and make money, is it not possible to: chemically or surgically weaken the Tunica and then pump?

If you could perforate the Tunica with 1000 tiny holes per square inch and then pump before it is healed you could evenly distribute the size gains.

There actually is a surgical PE technique where small incisions are made into the tunica and the force of erections alone leads to gains. I see it pop up from time to time in the surgery threads. I have no idea how well it works and I sounds really risky.

Originally Posted by all4show

Can you create a theory (similar to LOT) for the FSL and EL?

Here is an earlier attempt.


Enter your measurements in the PE Database.

Originally Posted by ModestoMan
Penismith,

For the record and to avoid devil’s advocacy :) , I don’t doubt the tunica is an important limiting factor. My point is that it is probably one of at least a couple. Inside the CCs, the smooth muscle operates within sinusoidal spaces made of collagen. Those spaces are defined by extensions of the inner layer of the tunica that form a lattice structure within the CC space.

My belief at the present moment is that length is limited by a combination of 1) tunica, 2) internal collagen structure of the CCs, 3) smooth muscle, and 4) other stuff (veins, arteries, nerves, skin …).

Guys whose BPEL is 2” longer than their FSL (which at least one guy has reported) are clearly not tunica-limited, IMO. They are somehow volume-limited. The contents of their CC cannot expand to fill the entire envelope that the tunica provides.

The point is, it’s all got to grow to realize BPEL gains.

Regarding the Peyronie’s article you posted, which I referred to above, it would be very interesting to see whether guys who received the venous transplants can continue to grow essentially at will by continuing to pump, or whether their growth is largely limited to just reclaiming lost length induced by the disease.

Oh no, not the Devil again. I still haven’t gotten over the last time you sicked the Devil on me. :p

It is possible that we don’t disagree. Smooth muscle is going to offer some resistance to the forces applied with PE. When I was doing extreme uli work, I had to do a lot of skin stretching and that didn’t happen overnight. My point is that tunica is likely a much greater limiting factor than the other penile tissues. Now don’t get me wrong, smooth muscle will certainly offer resistance, that is it’s job. My point is that if we focus on stretching the tunica, the smooth muscle is probably going to grow with it. If we focus on smooth muscle cell division, one of two things will likely happen: it won’t grow because of the tunica barrier or it will somehow send a growth signal to the tunica (that would be cool but I have no reason to believe it would happen). I don’t think that the pressure induced by smooth muscle growth will be sufficient to stretch the tunica, though.

I don’t know what to make of a 2” inch difference between BPEL and FSL. Forgive the skeptic in me but in-proper measurement, unusual physiology and differential relaxation of ligaments comes to mind. It could be that his smooth muscle is very tightly constricted but I am not sure there is enough smooth muscle there to resist the force generated by the arms and shoulders of an average man. IOW, we are putting a whole lot of skeletal muscle up against a little bit of smooth muscle. I think that the skeletal muscle is going to win. On the other hand, we know that collagen bundles have a tensile strength comparable to that of steel and when you put the skeletal muscle in the ring with the steel, the skeletal muscle is going to wear out before the steel gives, much.

Sorry, I missed your reply above. It was just a few minutes before my post.

Regarding the Peyronie’s article, yea, I agree that it would be interesting to see if they can surpass their original size. Are you sure that none of them do? I read the full text a long time ago. I will take another in depth look at it.

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