I’d worry about your health issue first then concentrate on your dick. PE can be very demanding and it could be hard to tackle both at the same time.
Yes, it’ll most certainly be hard, both physically and mentally, but at this point of my life I feel I must tackle them both head-on, or I’ll never do it once I start procrastinating (again). I did that, very successfully, for most of the past years. It’s time for a change.