Evidence that suggests that penile tissue can be grown by PE
Evidence of smooth muscle growth in PDMA patients and its implications for Penile growth
The esophagus is a muscular tube connecting the throat (pharynx) with the stomach. The esophagus is about 8 inches long, and is lined by moist pink tissue called mucosa. The esophagus runs behind the windpipe (trachea) and heart, and in front of the spine. Just before entering the stomach, the esophagus passes through the diaphragm. 
Peristaltic contractions of the esophageal muscle push food down the esophagus. These rhythmic contractions occur both as a reflex response to food that is in the mouth, and also as a response to the sensation of food within the esophagus itself. The muscular layer of the esophagus has two types of muscle. The upper third of the esophagus contains striated muscle, the lower third contains smooth muscle, and the middle third contains a mixture of both. Muscle is arranged in two layers: one in which the muscle fibres run longitudinal to the esophagus, and the other in which the fibres encircle the esophagus. These are separated by the myenteric plexus, a tangled network of nerve fibres involved in the secretion of mucus and in peristalsis of the smooth muscle of the esophagus. 
It is worth noting that smooth muscle cells have the greatest capacity to regenerate of all the muscle cell types. The smooth muscle cells themselves retain the ability to divide, and can increase in number this way. As well as this, new cells can be produced by the division of cells called pericytes that lie along some small blood vessels. Smooth muscle can also hypertrophy. 
The muscle fibers in smooth muscle are elongated cells containing a single nucleus. These cells can be replaced when smooth muscle is injured by trauma, surgery or disease. While during regeneration of skeletal muscle, only nearby precursor or satellite cells become activated and are the source of new muscle tissue, all smooth muscle cells have the ability to divide and form new smooth muscle. Muscle injury causes inflammation and release of soluble factors which stimulate surrounding smooth muscle cells to divide and replace the damaged cells. 
Primary disordered motor activity (PDMA) of the esophagus is characterized by abnormal motor activity in the lower two-thirds of the esophagus. Twenty-one patients with this syndrome were studied. Manometry showed a very severe motor disorder in the lower two-thirds of the esophagus. It was discovered that muscle hyperplasia (increase in number of smooth muscle cells) and motor spasm were present. Muscle hyperplasia resulted in the thickening of the esophageal wall. 
The key observation is that in 8 of 11 patients (72%) thickening of the smooth muscle tissue (hyperplasia) occurred in the presence of irregular motor spasms. This percentage is relatively high given that the condition is quite rare. One can infer that this expansion of the smooth muscle tissue could be due to the strong and often painful contractions caused by the spasms. These spasms involve vigorous contraction and relaxation of the smooth muscle tissue. A parallel can be drawn here with the jelqing technique employed by current penile enlargement exercises. Similarly, jelqing consists of vigorous manipulation of the penile shaft which induces hyperplasia in the smooth muscles of the cavernosa chambers. The growth of smooth muscle tissue in PDMA patients with strong motor spasms suggests that similar growth of penile smooth muscle could occur following mechanical stimulation of the penile shaft. Moreover, the rate of hyperplasia would be dependent on the frequency of stimulation and the intensity.
Further research into muscular hypertrophy/hyperplasia of the esophagus show comparable findings. ,,
Starting (8/05/2016): BPEL 5.7'', NBPEL 5.2'', MEG 5.1''
Current (10/02/2016): BPEL 6.0", NBPEL 5.3", MEG 5.15"
Goal: BPEL 6.5'', NBPEL 5.8'', MEG 5.3''
Last edited by XtaciLane : 09-19-2016 at .