Wellbutrin could help gains

Ya, ya, old post, but incase anyone cares, Wellbutrin has the same effect as a sugar pill:

SOURCE: Bupropion extended release compared with escitalopram: effects on sexual functioning and antidepressant efficacy in 2 randomized, double-blind, placebo-controlled studies.

RESULTS: In both the individual studies and the pooled dataset, the incidence of orgasm dysfunction at week 8 (primary endpoint) and the incidence of worsened sexual functioning at the end of the treatment period were statistically significantly lower with bupropion XL than with escitalopram (p < .05),

—-> not statistically different between bupropion XL and placebo (p > or = .067), <—-

and statistically significantly higher with escitalopram than with placebo (p < or = .001). The percentages of patients with orgasm dysfunction at week 8 in study 1, study 2, and the pooled dataset, respectively, were 13%, 16%, and 15% with bupropion XL; 32%, 29%, and 30% with escitalopram; and 11%, 8%, and 9% with placebo.

When I was on Wellbutrin my flaccid hung about 1 1/2 inches longer. I seriously have no idea why. I also noticed when hanging, stretching, and ADS’ing with PE weights that I actually felt fatigue for the first time ever. This makes me think my tunica is way too touch, retracted, and tight, which is how it feels most of the time. My erections were also MUCH harder on wellbutrin, I just had to stop taking it because I am a dedicated power lifter, and I was hardly eating, sweating nonstop, and it kind of killed my emotions.

Does anyone have any thoughts, or similar experiences? I am now looking for a way to get this back again without that drug.

Since you felt the need to start a new thread, I’m just gonna go ahead an quote myself.

ironaddict, equating your observation with possible PE gains seems like a stretch.
fourofakind, I don’t see what you are getting at with your quote. Your source simply shows that wellbutrin does not cause orgasm dysfunction or sexual dysfunction (nor would a sugar pill), while escitalopram can (which we know since it is an ssri). So, how is that related to the topic?

Yeah I’m with mravg on this one. Your post had NOTHING to do with mine. It is interesting how many rude people there are that like to chirp in on these threads.

How can a placebo cause sexual dysfunction?

Bupropion (INN; previously known as amfebutamone,[1] Wellbutrin, Zyban)…

…According to a survey, bupropion is the drug of choice among psychiatrists for the treatment of SSRI-induced sexual dysfunction…

…There are studies demonstrating the efficacy of both approaches; improvement of the desire and orgasm components of sexual function were the most often noted…

…Several studies have indicated that bupropion also relieves sexual dysfunction in people who do not have depression. In a mixed-gender double-blind study, 63% of subjects on a 12-week course of bupropion rated their condition as improved or much improved, versus 3% of subjects on placebo….

…

…According to a survey, bupropion is the drug of choice among psychiatrists for the treatment of SSRI-induced sexual dysfunction…

…There are studies demonstrating the efficacy of both approaches; improvement of the desire and orgasm components of sexual function were the most often noted…

…Several studies have indicated that bupropion also relieves sexual dysfunction in people who do not have depression. In a mixed-gender double-blind study, 63% of subjects on a 12-week course of bupropion rated their condition as improved or much improved, versus 3% of subjects on placebo….

Low sex drive affects at least one out of five women in the United States. A study presented at this year’s American Psychiatric Association meeting found that bupropion hydrochloride sustained-release tablets may be an effective treatment for some women who suffer from hypoactive sexual desire disorder (HSDD). There is currently no approved drug treatment for low sex drive in women.

Researchers found that almost one-third of the women in the study responded with increases in the number of episodes of sexual arousal, sexual fantasy, and interest in engaging in sexual activity. Women included in the study were aged 23 to 65 and had experienced HSDD for an average of six years. Participants saw improvement as early as two weeks after beginning treatment.

Bupropion hydrochloride SR enhances the presence of neurotransmitters, norepinephrine and dopamine, in the brain and is not associated with the sexual side effects often experienced by patients using selective serotonin reuptake inhibitors (SSRIs) anti-depressants such as Prozac, Paxil, and Zoloft.