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Prescription Medications and Penis Size

Prescription Medications and Penis Size

I was wondering if anyone has had experience with SSRI’s, dopamine agonists, or any other prescription medications affecting their penis size. Some PE’ers have blamed presription medications on size loss, while I have also heard that certain medications for mental conditions can cause penis growth. I know one side effect of SSRI’s is erectile dysfunction in some users, but I am talking about an actual loss or gain in erect penis size.

Any experiences would be appreciated.


I love GOLD

No, SSRI’s don’t affect size, neither gain or loss.


regards, mgus

Taped onto the dashboard of a car at a junkyard, I once found the following: "Good judgement comes from experience. Experience comes from bad judgement." The car was crashed.

Primary goal: To have an EQ above average (i.e. streetsmart, compassionate about life and happy) Secondary goal: to make an anagram of my signature denoting how I feel about my gains

Yeah, a cialis induced erection may be up to 10% larger than normal if you are very excited.

Sorry guys, it’s not permanent. But during those PCT times when things aren’t going well, I find that it is somewhat helpful for getting it up and when used in conjunction with PE can give positive results.

Other scripts like the antidepressants you mentioned. Sorry no personal knowledge. I’d have to agree that the previous poster is very likely correct.

I don’t have any proof, but after buying some Phentermine for weight loss I decided quickly to discontinue it. There is really something to the primal thing about a man holding a throbbing boner and feeling like a million dollars. After no erections for two weeks due to the phentermine, I have an increases sympathy for men with actual ED.

Originally Posted by mgus
No, SSRI’s don’t affect size, neither gain or loss.


Have you used SSRI’s, mgus? Particularly, I am interested in the dopamine affector drugs, such as haloperidol, pimozyde, etc. I also encourage discussion of ADHD drugs and other anti-psychotics.

Remember, I’m not concerned with erectile dysfunction, only actual growth or atrophy of the penis caused by prescription medications. Obviously, cialis and viagra will cause improvements in erection quality/size, but that isn’t the topic.


I love GOLD

Anything estrogenic like NSAIDs can affect erection and erection size, I’m living proof. This is not permanet after mot using them for awhile length returns, which is what I hope happens to me.
As far as meds for depression I don’t have any idea if they do or not.

Also antihistamines the kind that make you drowsy. They also cause weight gain. And lack luster woodies


Speak softly carry a big dick, I'm mean stick!

I have used and currently use Paxil. No atrophy or super growth.

SSRIs target they synapses in the brain and in the neurons in the stomach. There aren’t any neurons in your dick, regardless of the jokes about “the other head”. SSRIs exclusively target serotonin reuptake in the synapses. Nothing to do with smooth muscle, tendons, fascia or the like.


regards, mgus

Taped onto the dashboard of a car at a junkyard, I once found the following: "Good judgement comes from experience. Experience comes from bad judgement." The car was crashed.

Primary goal: To have an EQ above average (i.e. streetsmart, compassionate about life and happy) Secondary goal: to make an anagram of my signature denoting how I feel about my gains

Originally Posted by mgus
I have used and currently use Paxil. No atrophy or super growth.

SSRIs target they synapses in the brain and in the neurons in the stomach. There aren’t any neurons in your dick, regardless of the jokes about “the other head”. SSRIs exclusively target serotonin reuptake in the synapses. Nothing to do with smooth muscle, tendons, fascia or the like.


If there weren’t any neurons in your penis, you wouldn’t feel a damn thing during sex, or ever.

There may not necessarily be a direct effect of serotonin on the penis, either. There may be some other metabolic pathway affected by the decrease in serotonin reuptake.


I love GOLD

Originally Posted by kingpole
Anything estrogenic like NSAIDs can affect erection and erection size, I’m living proof. This is not permanet after mot using them for awhile length returns, which is what I hope happens to me.
As far as meds for depression I don’t have any idea if they do or not.

Also antihistamines the kind that make you drowsy. They also cause weight gain. And lack luster woodies


I doubt that NSAIDS are estrogenic. There negative effect on erections is most likely due to their inhibition of CoX-2, which is responsible for prostaglandin production.


I love GOLD

Originally Posted by gold_member
I doubt that NSAIDS are estrogenic. There negative effect on erections is most likely due to their inhibition of CoX-2, which is responsible for prostaglandin production.

I actually read that they are, this list includes Tylenol as well. But I forgot the name of the author of the book. Tittle, Testosterone something I’m going to go check it out of the library again.

To what degree they are estrogenic I do not know. However I also read that Vitamin “C” and Zinc can block some of the estrogenic affect. There again I would not know how much to take to offset this side effect.

I have considerable shrinkage from ibuprofen, I was taking it for sciatica. Perhaps the pain is also a factor in the bit of shrinkage which I’m working to bring back.

Antihistamines is a girth robber for sure.

Have you noticed any shrinkage from taking SSRI’s? What you got to watch out for with depression drugs is weight gain, that is adipose tissue.


Speak softly carry a big dick, I'm mean stick!

Originally Posted by gold_member
If there weren’t any neurons in your penis, you wouldn’t feel a damn thing during sex, or ever.


You’re right. I was trying to say that there is no grey matter in the dick. There are of course nerve endings etc that transport sensory information & instructions back and forth. I can’t see that more or less serotonin can change growth of fascia, muscle etc.

On the wiki about SSRI’s the following can be read (Selective serotonin reuptake inhibitor - Wikipedia)

Quote
[edit] Cardiovascular Side Effects
SSRIs inhibit cardiac and vascular Na(+), Ca(2+) and K(+) channels and prolong QT intervals. These results suggest that SSRIs have clinically important cardiac as well as vascular effects. Clinicians should be more vigilant about these potential adverse reactions and ECG control may be suggested during therapy, especially in patients with cardiovascular disorders.[7] [8]

Vascular resistance is modulated in a complex fashion by serotonin receptors. In healthy people, serotonin causes vasodilation. For example, in the cerebral arteries, the 5-HT1 receptor causes vasoconstriction, which is why sumatriptan succinate (a 5-HT1 agonist) can be used in the treatment of migraine headaches. Serotonin also plays an important role in angina. While serotonin has a vasodilatory effect on normal coronary arteries (an effect that is blocked by the 5-HT2 receptor antagonist ketanserin), serotonin produces direct unopposed vasoconstriction in damaged endothelium. In patients with damaged endothelium (such as those with significant coronary artery disease), it has been speculated that there may be an increase in myocardial ischemia secondary to an increase in vasoconstrictive serotonin in the environment caused by treatment with SSRIs.[9]

In the first 2.5 million patients exposed to fluoxetine, there were reports of 34 cases of atrial arrhythmias, 60 cases of bradycardia, 26 cases of varying degrees of heart block, 54 cases of significant ventricular arrhythmias, 24 cases of congestive heart failure, and 42 cases of other arrhythmias [10]

Cardiovascular events associated with SSRI use include cardiac arrhythmias, orthostatic hypotension, atrial fibrillation, atrial flutter and supraventricular tachycardia. In overdose, fluoxetine has been reported to cause sinus tachycardia, myocardial Infarction, junctional rhythms and trigeminy. However, the total incidence of adverse cardiac effects has been indicated to be less than 0.0003 percent.[11]

The one thing I can find that might affect is the vasodilation part above - that SSRI’s seem to act as vasodilators in some cases, as vasoconstrictors in others. But on the other hand, if the incidence of problems is less than 0.0003 %, it should be OK.


regards, mgus

Taped onto the dashboard of a car at a junkyard, I once found the following: "Good judgement comes from experience. Experience comes from bad judgement." The car was crashed.

Primary goal: To have an EQ above average (i.e. streetsmart, compassionate about life and happy) Secondary goal: to make an anagram of my signature denoting how I feel about my gains

Originally Posted by kingpole
Have you noticed any shrinkage from taking SSRI’s? What you got to watch out for with depression drugs is weight gain, that is adipose tissue.


I haven’t noticed any shrinkage. I’ve taken Paxil and efexor.

Weight gain may be adipose tissue, whatever that is, but my experience is that as mood increases so does appetite. Depression takes the edge off of hunger.


regards, mgus

Taped onto the dashboard of a car at a junkyard, I once found the following: "Good judgement comes from experience. Experience comes from bad judgement." The car was crashed.

Primary goal: To have an EQ above average (i.e. streetsmart, compassionate about life and happy) Secondary goal: to make an anagram of my signature denoting how I feel about my gains

Originally Posted by mgus
….my experience is that as mood increases so does appetite. Depression takes the edge off of hunger.


I would have to say the opposite for me. If I’m in a great mood, I usually don’t feel like eating “comfort foods”. (Think fat chick settling down with a gallon of ice cream to make herself happy). I think the weight gain is because the SSRI’s make you tired, and less likely to exercise. BTW, adipose is just another word for fat tissue.

What is your dosage of paxil, mgus?


I love GOLD

20 mg.

No, for me it’s quite definitely that depression / dystymia robs me of hunger sensations. Paxil doesn’t really give me a lust for comfort foods, mostly just a healthier appetite. Kind of like more interest in food along with general zest for life. Might be that I am a bit more tired too.

One side effect is that my resting pulse is much higher.


regards, mgus

Taped onto the dashboard of a car at a junkyard, I once found the following: "Good judgement comes from experience. Experience comes from bad judgement." The car was crashed.

Primary goal: To have an EQ above average (i.e. streetsmart, compassionate about life and happy) Secondary goal: to make an anagram of my signature denoting how I feel about my gains

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