Nootropics

I take my selegiline in the morning, or at least whenever I wake up. I actually tend to sleep better, but largely because it seems to lessen my restless legs symptoms. I take modafinil most days which tends to suppress my appetite, so I can’t weigh in on whether selegiline affects that.

Thanks so much. Bromocriptine, mirapex, all those really put my appetite down too.

Dopamine is also responsible for the gag/nausea reflex to some degree, so it could cause appetite suppression through you being less able to stomach the idea of food.

I have some pramipexole on the way to try out, hopefully the longer half-life will make it an easier night-time RLS help than levodopa. I’m still researching this, but anecdotally have any of you found potentiation between selegiline and prami?

Restless Leg Syndrome - Symptoms, Diagnosis and Treatment

If you read a physical book on Magnesium, you can see where Mag loss causes a cascade in 325 other reactions bit by bit. You can google RLS+magnesium and find tons of data.

@RDopa, no not at all.., On another note - it appears that liquid Selegiline, (Selepryl), is no longer being made, and the alternative Denepryl, (a tablet), will be the norm..

Oh my god I am heterosexually in love with you right now. I have had that for YEARS and wondered if that was the cause. I gag just laying down on the bench press.looks like my bromocriptine dosage needs to come down. Thanks again!

twatteaser: I take magnesium daily, it hasn’t seemed to have effected the RLS symptoms which appeared after a particularly horrific withdrawal from SSRIs, I’m starting to think there may have been some permanent change to my dopamine neurons. Magnesium stops me from getting hangovers though.

Have you looked into perhaps the vector of the magnesium would make it better? All the pop med books I read endorse different types. Mg Sulfate, Mg Chloride, Mg Chelate, etc….

I ended up buying a supplement that had three different types, I think it’s the aspartate form that has the greatest effect.

Just started today with a 5 mg tab, I will keep everyone posted. I have had a pretty low sex drive recently for a specific reason, and if this stuff bounces me back I will KNOW it is powerful.

Anyone noticing a stimulant effect or losing weight/appetite reduction while on it?

Whoa - @Ironadict69 - may wanna start of slow and allow the system to get used to it - it’s *very* powerful and going from nothing to 5mg will certainly get your system’s attention and not in a good way…

I have noticed I am losing both visceral and abdominal weight on this stuff..

Good luck!

Yeah backed down to 2.5 mg today and will stay there.

Any updates from the testers of Selegiline? Oz, Ironaddict69, LordAaron. Any news or updates to report on the results? Thx

Yup - Am on 2 drops every morning of liquid Selegiline.. No changes other than what I have written before.. Soon though am moving onto the tablet form as I have been unable to source the liquid form anywhere. The new dosage will be 2.5 mg every morning sublingually.

An aside, (now) wife, who was on 1 drop per day, started to drop into bouts of (very) mild depression. I suggested she discontinue, and is now fine again.. Considering we only just got married with all the attendant stress involved it’s hard to tell what was the cause though.

I’m still able to easily control abdominal and visceral fat levels with little to no change in diet :) , energy levels remain the same as well.

Be Well

Oz