Erectile Dysfunction & NSAIDS
As I’m sure you all know the class of drugs listed as NSAIDS is one of very commonly used pain killers and includes: Aspirin, Tylenol , Ibuprofen (Asvil and Motrin), Alleve , Indomethacin and some others I have not named here.
Point is that these drugs are now being connected with an increase in Erectile Dysfunction. They all act as Antiprostaglandins.
Prostaglandins are found throughout the body and when a person suffers an injury the pain is thought to be from the release of Prostaglandin.
Consider the following: Caverject by Wyeth is an intracavernosal injection of Prostadyl which causes erections. All the Trimix intracavernosal drugs contain Prostadyl along with other chemicals such as apomorhine and Phentolamine.
In the premature newborn, if the circulation after birth continues to shunt blood around the lungs through an artery called the Ductus Areriosus, the trreatment is to inject Indomethacin which closes the ductus. In other words an antiprostaglandin is used to constrict an artery
Could the same thing be happening to the penile artery?
Good question . And food for thought.