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Viagra

Viagra

I’ve asked other doctors about Viagra, they’re actually surprised how I know all the intricate ways it works, but I’m still a bit confused, I have yet to get an answer to it. Maybe someone else on here has the knowledge.

When an erection happens Nitrous Oxide is released. When NO is released cGMP is then released and relaxes the smooth muscles to allow more blood flow. However PDE5 degrades cGMP. Viagra inhibits PDE5, so the erection will not ‘go down’. However the erection CAN go down, if one changes their thoughts or mood while having the erection. So I’m just confused if you inhibit the very thing that allows the erection to go down, what ELSE allows the erection to go down? What is even the point of having PDE5 in our bodies, if seems to have no use but cause impotence. Anyone shed more ligt on this??

Also, I guess I’d assume that maybe Viagra only inhibits SOME of the PDE5 thus allowing an erection to be sustained for little longer? However if all the PDE5 were to be inibited the erection would probably last forever? Has anyone even had priapism from Viagra (with ed or not)?

I don’t mind if whomever knows gets down to the nitty gritty of what Viagra does.

We have PDE5 in our bodies to keep us from having inappropriate erections. There are so many occasions in life when having an erection would be unsafe (working with power tools - ouch!), or embarrassing (when your Gramma is standing in your kitchen talking with you), or when you are on stage doing a Power Point sales pitch. The article pinned to the top of the Men’s Sexual Health forum, Men’s Sexual Circuitry, explains the subtle interplay of the sympathetic and para-sympathetic nervous systems and how they act to encourage and discourage erections.

You sort of hit the nail on the head in pointing out that Viagra erections will go down when stimulation, mental or physical, stops. But once the stimulation resumes, there is plenty of available nitric oxide to get another going, as well as some other chemicals that operate to get us hard.

During the time Viagra is working for you, it does continue to suppress PDE5. It’s adrenalin, prolactin, and other chemicals and nervous system interactions that allow the erection to deflate or inflate, depending on the circumstances.

Although the Viagra commercials keep reminding us that an erection lasting more than four hours is not good - every time I see that I imagine a chorus of American males saying “And why the hell not??” - priapism is not common with this drug unless you take more than you should or you have some physical condition making you prone to events of priapism. When the drug first came out, a young, naive medical resident in Boston, I believe it was, who did not have ED, took 200 mg of V and ended up in his own emergency room having blood drained out of his cock.


_______________

avocet8

Hmm thanks, informative. That 200mg’s must have eliminated close to all of his PDE5’s. I’m only 23, I’d assume 25mg’s would not cause anything adverse at that dose?

Probably not. But do you really need it?


_______________

avocet8

Actually it seems to be a clinical study conducted by an German urologist. This study (presented at varios urological congresses around the world) performed on several males of different ages without ED concluded that a daily intake of about 50-100 mg. of Tadalif nightly (prior to sleep) is beneficial because promotes stronger erections and helps to prevent ED in advanced ages. Because stronger nocturnal erections seems to be beneficial to the endotelial tissue of the corpora cavernasa and the overall vascular sistem of the penis chambers.

Remember always to ask a doctor if you can take Viagra or similar drugs. If this is the case, medical evidence says a daily use of Tadalafil, Sildenafil or Verdanafil in a controlled way of dosage is not dangerous and, in fact, promotes a better sexual performance and a better overall penis health.

But, as with any other medicine, you should visit first a doctor in order to know if you really can take Viagra or similar.


Last edited by Mr. Happy : 10-02-2007 at . Reason: German for german

Where is this study?

:)

That’s a bad thing?

On second thought, I went to the beach this summer. It could, indeed, be a very bad thing.


Before: I'd like to show you something I'm very proud of, but you'll have to move real close.

After: I\'d like to show you something I\'m very proud of, but you guys in the front row will have to stand back.

God gave men both a penis and a brain, but unfortunately not enough blood supply to run both at the same time. - Robin Williams (:

Originally Posted by refresh9

I’ve asked other doctors about Viagra, they’re actually surprised how I know all the intricate ways it works… When an erection happens Nitrous Oxide is released.

Apparently you think you know more than you actually do. It’s nitric oxide (NO). Nitrous oxide (“laughing gas”, N2O) is a gas that has analgesic and weak anesthetic properties and is also used to increase the power of the burned fuel in internal combustion engines by adding oxygen to the mix.

Good catch, westla.

As usual, you’re showing the rest of us up. :up:

:)


Before: I'd like to show you something I'm very proud of, but you'll have to move real close.

After: I\'d like to show you something I\'m very proud of, but you guys in the front row will have to stand back.

God gave men both a penis and a brain, but unfortunately not enough blood supply to run both at the same time. - Robin Williams (:

I don’t have a link to the study I quoted, because I read about it on a medical newspapers distributed in the Hospital where I work at. But I think it’s real, because it’s information for doctors.

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