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The Chemical PE Thread

Relaxin promotes growth of reproductive tissues…

Then it goes on to say they dont know how… But that they did find that a relationship exist between HR2 and IGF-1 and IGF-2.
http://www.ncbi.nlm.nih.gov/pubmed/9275049

This hits at my intuition… I suspect this not fully understood process of just how relaxin causes general morphological changes to genitalia is where IGF-1 and IGF-2 play a key role in this mystery process.

Thats why in my latest experiment I took a dose of 6.5mcg of PGE-1, waited to get hard then put on a rubber ring on after I injected 3cc’s of HR2, IGF-1 LR3, and IGF-2LR3. 1 cc of each.

HR2 is 1 vial 5mg into 20cc of Bac H20, IGF-1 is 100mcg in 10cc and IGF-2 is 1200mcg in 20cc. These are my concentrations.

Anyway after injected I put on the o-ring and pumped in warm bath water at 200 on the gauge for 15-20 minutes. Then after I got more limp after 1.5 hrs or so I put on my PeniMaster and pulled till bed time a few hours later…. No jelqs, no clamping save whilst pumping if you want to count that.

Inuic

Does anybody do this chemical PE stuff with pumping ? I would love to hear about gains in girth. Permanent gains.


1/15/2014 - 7.5 BPEL x 5 MSG

3/28/2014 - 7.5 BPEL x 5.1875 MSG

2/20/2015 - 7.75 BPEL x 5.25 MSG

My recent clamping results are very promising. With several very painful >10h PGE-1 hangover erections, you’d however have to know your physical limits very well.


Sssnrgd..

.Clickdiclack.Rrndhgzzirp..

."Wow!"*

I Like to particularly pump after I clamp then inject, with my oring on in the water pump. I do Relaxin and the IGF 1 and 2 this way.

inuic

I’d like to believe there’s still a lot of benefit to the “vascular occlusion” theories mentioned during the original wave of ChempPE trials. Seems like an important part of the equation that not too many really tried.

Nobody has answered the question


1/15/2014 - 7.5 BPEL x 5 MSG

3/28/2014 - 7.5 BPEL x 5.1875 MSG

2/20/2015 - 7.75 BPEL x 5.25 MSG

Sorry, for my part, I have given up pumping long time ago, for the lack of permanent gains.

Seems like the intersection of chemical PE practitioners and pumpers is slim to non-existent.


Sssnrgd..

.Clickdiclack.Rrndhgzzirp..

."Wow!"*

4myExistence,

You asked about ChemPE and pumping. Well I tried to answer above, and will try again here. Yes I do both these, ChemPE and Pump, both alone and together. I do so for several reasons. One is the comfort, it is simply easier to sometimes with PGE-1 to be in warm water, it helps with the PGE-1 burns. And Pumping allows me to not feel this as much either, especially with hot water. Also I hypothesize that placing a tight rubber ring at the base of your penis while pumping and before injecting and while on PGE-1 especially help keep more of the peptides where I want them. I also hypothesize that while producing states more approximal to hypoxia certain growth factors like VEGF will be more present and micro sites in need of healing from the over balooning of the CC tissue which I think attract agents of healing like IGF-1 or what have you more so to the sites.

So I pump to help trap and localize my injections in my penis. Also after while I am more swelled up after pumping with warm\hot water my penis is more supple and ready to stretch. And while on PGE-1 it stays that way for awhile and during that time I am stretching via my penimaster. I used to use a phallosan and may still like that in ways but in other ways not. I like the full rubber sleeve of the phallosan because it help maintain a fuller vacuum on my penis after I pumped at the more fuller volume. But semi erect stretching while super warm is good I believe. Sometime I keep the oring on while stretching like this for 15 min max, to keep plump while stretching. I think that helps elongate and stretch the tissue.

Also it was recommended with my PRP shots. The idea is give something to help activate the platelets via strong pumping and micro liesons and to create a something for the Fibrin matrix to fill into. After I got my PRP shot I was asked to pump right after. This was to max out my volume while the prp formed the fibrin matrix with my past normal volume as the frame\scaffold for the matrix to fill into and heal out into. I assume something is going like this also with TB4, as its the most like PRP of all the peptides when you get the good stuff. I pump a whole vial of TB4 into the CC when I do that.

inuic

Oh yes I use a water pump with a gauge\meter. I try to stay between a 100 and 200 on the meter…. for 15 min max… GirthMaster…

Thank you for your reply. Chemical PE intrigues me. How long has this concept been around? So it’s all about inducing an extreme erection to get better internal expansion ? Is there anything else to it ? Anybody reading this should share gains and quick summaries of their routine so we can better evaluate the advantage of chemical PE.


1/15/2014 - 7.5 BPEL x 5 MSG

3/28/2014 - 7.5 BPEL x 5.1875 MSG

2/20/2015 - 7.75 BPEL x 5.25 MSG

4myExistence, what people are mainly talking about when they talk about “ChemPE” goes back, most prominantly, to a patent owned by a Dr Adams in Canada. Do a search for that if you would like some good background. There also is a guy named Ronielle who has done a lot of experimentation on himself with it.

Originally Posted by 4myExistence

Thank you for your reply. Chemical PE intrigues me. How long has this concept been around? So it’s all about inducing an extreme erection to get better internal expansion ? Is there anything else to it ? Anybody reading this should share gains and quick summaries of their routine so we can better evaluate the advantage of chemical PE.

Read the first post! It answers most of your questions. Either directly or via its links to lots of other resources.


Sssnrgd..

.Clickdiclack.Rrndhgzzirp..

."Wow!"*

I’ve recently been thinking about how, from what I’ve seen based on various postings, it can be complicated getting the proper amount of erect time. That led me to researching whether any popular vasodialators work in combination with the compounds at hand to provide any particular benefit, while also increasing erect time. I’m not too deep into said research, but I’m just trying to connect any dots I can. Most of this I’ve seen posted before in various spots, but figured I’d post my findings.

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DHT and NO/Viagra-like compounds:

http://www.ncbi.nlm.nih.gov/pubmed/7534702

“These results show that DHT is the active androgen in the prevention of erectile failure seen in castrated rats, and suggest that this effect may be mediated, at least partially, by changes in nitric oxide synthase levels in the penis.”

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Papaverine increases cyclic AMP, synergises with PGE2.

http://www.ncbi.nlm.nih.gov/pubmed/10810351

-“Papaverine combined with prostaglandin E2 synergistically induces neuron-like morphological changes and decrease of malignancy in human prostatic cancer LNCaP cells.”

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L-Arginine and Relaxin:

http://www.ncbi.nlm.nih.gov/pubmed/9622136

-“This study suggests that RLX is an endogenous agent capable of regulating vascular tone by activation of the L-arginine-NO pathway in vascular smooth muscle cells.”

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L-Arginine and IGF:

http://www.ncbi.nlm.nih.gov/pubmed/16923367

-“L-arginine can increase the levels of IGF-I and IGF-II and the IGF-I mRNA expression in the brain of rats with IUGR”

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L-Arginine, Vardenafil, VEGF:

http://www.ncbi.nlm.nih.gov/pubmed/18331270

-“CCSMCs express eNOS and synthesize NO. NO synthesis leads to enhancement of VEGF synthesis via the NO/cGMP pathway. Combined L-arg and vardenafil treatment, which can enhance VEGF production.”

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L-Arginine, NO, VEGF:

http://www.ncbi.nlm.nih.gov/pubmed/23649256

“Our data indicate that NO induce VEGF expression in vivo and in vitro in the rat placenta, suggesting that peaked NO production was maintained by a reciprocal relationship between NO and VEGF via HIF-1α.”

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L-Arginine and VEGF, Angiogenesis after exercise:

http://www.ncbi.nlm.nih.gov/pubmed/16779912

“The present results suggest that in middle-aged rats, L-arginine administration caused additional effects on exercise-induced angiogenesis by presumably promoting VEGF expression”

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Vardenafil, Angiogenesis/ischemia, VEGF, etc:

http://www.ncbi.nlm.nih.gov/pubmed/20413734

“Vardenafil .. Augmented capillary collateral formation in ischemic muscle. Vardenafil upregulated protein expression of vascular endothelial growth factor and hypoxia-inducible factor (HIF)-1 alpha in ischemic muscle and enhanced mobilization of Sca-1/Flk-1-positive endothelial progenitor cells (EPCs) in peripheral blood and bone marrow, contributing to neovascularization. Vardenafil also promoted capillary-like tube formation of human umbilical vein endothelial cells” .. “PDE5 inhibition enhances ischemia-induced angiogenesis .. Through a protein kinase G-dependent HIF-1/vascular endothelial growth factor pathway”

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Oxytocin: One international unit (IU) of oxytocin is the equivalent of about 2 micrograms of pure peptide.

Nice to know…

It has other mysteries in store for our odyssey…

One is it connection to NO production…. Among other things…

But if you are using it that conversion might be useful…

These are some interesting studies, you brought together, Atmospheric! Thanks for sharing your research!


Sssnrgd..

.Clickdiclack.Rrndhgzzirp..

."Wow!"*

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