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Raw Tadalafil powder Cialis powder

Well, RG, it’s cool. Get it into your system real well. Then taper to what you think will be a good scheduled dosage.

At your age, doing near/somewhat of a max dose. 10mg-15mg every other day! You’ll find your own scheduling deal.”the side-effects if any, will help you choose a dosage”.

RG ,I don’t get the heartburn every time. About half the time I would say. It doesn’t usually bother me too much and goes away in a short while. I did get the burn so bad from liquid Levitra that I could not have had sex on it. Even if it would have made me hard. I don’t respond to Levitra very well. Anyway, back to the heartburn thing, as webby suggested maybe 10 mg every day as opposed to 20 every other.

yo RG, I ordered from Elitenet a couple months ago. You really have to watch for the overdose…I got really bad hip pain it was terrible. Its all good now, and I’m about ready to remeasure doses so that problem won’t happen again (it was a problem with the doses). Even a lick, the tiniest amount u can even see can be too much when you’ve already taken some. My point is make sure you measure everything well.

My next visit to the doc, i’m gonna see if I can get some Viagra. I hear and have read on Thunders that you can get like 120% erection size.


I’m amazed at times of the various side effects folks get and have been searching about for responses to Levitra.

Seem’s Levitra isn’t doing so great. Appears the side’s are more prominent with Levitra as to L & C.

In my case, over 15 mg Levitra and I’m worthless for sex or much else! Cialis, after taking 20+mg daily, after awhile I begin to get back cramps! Levitra, over ? 15mg and the stuffy nose, shitty feelings, etc, is very bothersome.

I take some form of gastric med “Prilosec, Previcid, Nexium” so the heartburn, can’t tell if any give me heartburn.

Originally Posted by ChuckR
Siva, thanks for the info on Ora-Plus. I see there’s also a premixed version of Ora-Plus and Ora-Sweet (50/50) called Ora-Blend.

How do you think this would compare with using propylene glycol? Or maybe a propylene glycol and vodka mix? I guess the Ora-* stuff is preserved in some way.

Yes, Ora-Blend is a 1:1 blend of Ora-Plus and Ora-Sweet. It is more convenient and overall has less up-front costs since you only have to buy one bottle. Can definitely be used in the pharmaceutical compound that I described. As far as comparison with propylene glycol and ethyl alcohol, I don’t really know.. The Ora-“X” products contain methylparaben and potassium sorbate as preservatives. Also, traditionally, high-sucrose syrups have preserving qualities. The Ora-“X” product would probably taste alot better.

I couldn’t find any pharmaceutical information using propylene glycol as a suspending agent for any of the PDE5 inhibitors. Tadalafil is not soluble in water and only slightly soluble in ethyl alcohol. I’d be interested in knowing how well tadalafil dissolves in pure propylene glycol. If it is very soluble in propylene glycol, then it would make an excellent wetting agent which can then be used in suspensions. Hmmmm.. Sounds like an experiment for me to try? Anyone else have experience using propylene glycol with tadalafil? What does the resultant product look like? Clear? Cloudy? Any sediment or precipitate?

Originally Posted by RandomGiant
Well, 30 seconds before reading the responses of webslave and siva I took a 20 mg dose :) .

If I get side effects again I’ll stick with 10 mg per day. Thanks guys.

RG, did you get any side effects with 20mg? I usually get a little sinus congestion with 10 to 15 mg of tadalafil. I never got any myalgias.

I’m still a little stiff from my 25 mg dose, but I don’t think I got any sides from 20 mg. I actually ended up getting pretty drunk last night. I remember hearing that drinking and Cialis don’t mix, do the sides get worse or does it cancel out the effect?

Still I’m thinking about taking 10 mg a day to see how my body reacts to that.

RG, tadalafil can potentiate the hypotensive effects of alcohol (vica-versa) and cause your blood pressure to drop. The prescribing information on Cialis states (>5 units of alcohol). I don’t exactly know what 5 units is? 5 shots? 5 beers? 5 glasses of wine? Probably all would suffice as 5 units. Alcohol causes venous dilation, so it has a negative impact on erection quality because of increased outflow. If the alcohol-tadalafil hypotension is very severe, it can cause cardiovascular collapse (which is what happens when you mix nitrates with PDE5 inhibitors). BUT, interestingly enough, tadalafil is more specific with PDE5 than with the other PD enzymes (see attachment). Tadalafil is much less specific to other PD enzymes than sildenafil or vardenafil, so in theory it should have less potential for serious side effects (ocular, cardiovascular, muscular, etc.). BUT this is only in theory! There should be a double-blind comparative study looking at these adverse reactions to see if tadalafil does indeed have less “major” side effects.

Regarding daily tadalafil usage check out:

Http://www.cialis.com/common_pages/pressrelease.jsp

Attached Files

Good post Siva. Nice to have you on board.


Horny Bastard

Yeah, and thanks for the heads up.

Yea

Originally Posted by RandomGiant
I actually ended up getting pretty drunk last night. I remember hearing that drinking and Cialis don’t mix, do the sides get worse or does it cancel out the effect?

Still I’m thinking about taking 10 mg a day to see how my body reacts to that.

Drinking pretty much reduces the effects of tadalafil greatly I believe.

And, yes, do the 10mg daily and let us know how it works for you.

Originally Posted by skepticknight
Webslave, thanks for your posts and website. I just ordered some Tadalafil powder (2g) and am getting 16 100mg tabs of Sildedafil tabs (2 4x paks of each of their India name brands) too from elitenetpharm. Will post results. Felt much better reading around, in particular your sharing of experiences with them.

I received my order on the 8th, so it came pretty quick (ordered the 28th). I still need to figure out what to do with the Tadalafil powder but did take 50mg of the Progra Sildenafil Citrate.broke one 100mg in half. My wife and I were sharing a cabin with some friends but it magnified all sounds so we went for a quick ride in our mini van. My wife and I haven’t had such good sex in years, she said she hadn’t it felt so hard in years. I really felt like I was even penetrating her more than before too. In her own words: “that medicine rocks”.I’m still buzzing about how good it was for us and that was Sat night!

I’ve taken viagra before, always liked it, very pleased with my order from Elitenetparmacy. I can’t wait to do it again. I have been dieting and exercising a lot and have been having trouble keeping it up.no more.I am certain this performs better than even before I was having problems!

Siva, I wonder if it might be better to use a liquid in which tadalafil does NOT dissolve. As I see it, the major questions are: preventing things from growing in the suspension, and preventing the compound itself from degrading - either from oxidation or from reaction with something in the liquid.

And it would be my guess that a compound that’s reactive with other things might be even more reactive in solution. Does that make any sense?

Anyway, thanks to a local compounding pharmacy, I now have 60 ml of Ora-Plus. And I already had a bottle of propylene glycol. And, amazingly enough, I have plenty of vodka. :-) So I have an embarrassment of options.

I don’t know how “preserved” PG is. Ora-Plus of course is preserved, but is mostly water. It’s just not clear to me which would be best, or whether it would make sense to use a combination of both.

The 2 gm of powder would last me almost a year, so whatever liquid I use needs to be anti-microbial and chemically inert to tadalafil for a long time. It would be easiest to mix the whole 2 gm with liquid to start with, so I don’t have to divide it up, and then draw off maybe 20 ml at a time from which the actual dose could be drawn.

I’m kinda tempted to mix the 2 gm of powder with the 60 ml of Ora-Plus, which would give me 33.33 mg per ml, which works fine for me - it would be .6 ml per 20 mg dose, but I just don’t have a feel for whether something in the Ora-Plus might be reactive with tadalafil.

Here’s a link to a .pdf showing the ingredients in Ora-Plus.

http://www.paddocklabs.com/forms/msds/oraplus.pdf

Nothing in the Ora-Plus would cause any “break-down”. Basically water and binder’s. Does it have a pleasant taste ? Perhaps add a touch of ethanol / vodka to discourage bacterial growth.

Originally Posted by ChuckR
Siva, I wonder if it might be better to use a liquid in which tadalafil does NOT dissolve. As I see it, the major questions are: preventing things from growing in the suspension, and preventing the compound itself from degrading - either from oxidation or from reaction with something in the liquid.

Tadalafil does not dissolve in Ora-Plus or Ora-Sweet, that is why the resultant product is a “suspension”. Making the potential product a “solution” versus suspension would make it “easier” to make a more concentrated product, similar to the concentration that you described. My bias is that a “better” suspended product would have more suspending agents to “surround” it. That is why the concentration of tadalafil in the formula I described is 20mg/5ml and not 20mg/ml. Not to say that a 20mg/ml product isn’t feasible, just not commonly used in pharmaceutical practice.

The compound that I have described has sufficient preservatives in it to prevent microbial growth. The addition of Ora-Sweet also adds preservative qualities because of the high sucrose content. Stability studies with sildenafil show that very little degrades over a 90 day period (about 1mg) using this recipe. Refrigeration does not provide any additional stability benefit. It seems like you’d be doing something different, so I couldn’t really comment on whether or not it would be a suitable suspension or adequately preserved. It probably would be adequately preserved, but I’m not quite sure if the more concentrated formula (33.3mg/ml versus 20mg/5ml) would be adequately suspended.

To answer your question: PG is NOT preserved. I imagine that the vodka would act as the “preservative” if you were to use it. Ora-Plus is mostly water, but most suspensions are just that. The methyl-cellulose derivatives act as the “suspending agents”. Ora-Plus has methylparabens as an antimicrobial and potassium sorbate as an antifungal agent.

I would NOT worry about Ora-Plus “reacting” with tadalafil. The formula that I have described has been officially studied for stability and found to be VERY stable. My only question would be whether or not your product would be adequately suspended. But, if you shake very well before each use and inspect to see if there is any sediment on the bottom of your bottle, then you’d probably be OK.

I have another report on ChemOne. Last night I took .3 ml (less than 10 mg) and woke up with some bad side effects! In the middle of the night it felt like my blood pressure was way too low and that I was going to pass out at any second. When I woke up fully, I had a rock-solid erection and it felt like my sinuses were getting ripped off every now and then. It’s odd because this is a low dose that I’ve been taking for a while and hadn’t dosed in the past three days. Perhaps I just got a more concentrated dose?

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